Now in its third edition, this extensively revised Oxford Textbook of Osteoarthritis and Crystal Arthropathy brings together a prestigious and international author team in the definitive guide to these conditions. A practical resource for clinicians and health professionals managing people with osteoarthritis, gout and other crystal associated arthritis, this book provides up-to-date comprehensive guidance on how to assess, diagnose and optimally manage patients with these common joint diseases.
The Oxford Textbook of Osteoarthritis and Crystal Arthropathy provides full coverage of joint failure, allowing the physician to consider and choose the right blend of treatment from the range available, whether physical, pharmacological, surgical or supportive. Including detailed sections on epidemiology, risk factors, clinical assessment and investigations, significant coverage is also given to patient education and the involvement of the patient in management planning. With critical appraisal of current guidelines and a clear overview of pain physiology, the Oxford Textbook of Osteoarthritis and Crystal Arthropathy brings current understanding of these disorders together into a critical and highly valuable resource. Highly illustrated and in full colour throughout, this essential text is an important tool for rheumatologists and musculoskeletal health professionals. Now including new sections on gout and other crystal arthropathies, this fully updated edition focuses on clinically relevant and easily understood overviews of osteoarthritis.
1. What is Osteoarthritis? 1: Michael Doherty, Nigel Arden, Johannes Bijlsma, Nicola Dalbeth and David Hunter: What is Osteoarthritis? 2: Juliet Rogers and Paul Dieppe: Paleopathology 3: Laura A. Stoppiello and Michael Doherty: Morphological aspects of pathology 2. Tissues 4: Peter M van der Kraan and Esmeralda N Blaney Davidson: Cartilage 5: Steven R. Goldring and Richard L. Menschel: Pathophysiology of peri-articular bone changes in osteoarthritis 6: Floris Lafeber, N.J. Besselink and S.C. Mastbergen: Osteoarthritis: synovium and capsule 7: Jason J. McDougall and Joel A. Vilensky: Neuromuscular 3. Epidemiology 8: Nigel Arden and Michael C. Nevitt: Epidemiology 4. Risk factors 9: Ana M Valdes: Genetics 10: Joanne M. Jordan, Kelli D. Allen and Leigh F. Callahan: Age, gender, race/ethnicity, and socioeconomic status in osteoarthritis and its outcomes 11: Richard Aspden and Jenny Gregory: Morphology 12: J. Runhaar and S.M.A. Bierma-Zeinstra: Lifestyle 5. Pain 13: Philip Mease: Neurobiology of pain in osteoarthritis 14: David A Walsh: Contextual aspects of pain; why does the patient hurt? 6. Clinical assessment 15: Margreet Kloppenburg: Clinical assessment: signs, symptoms and patient perceptions in osteoarthritis 16: Daichi Hayashi, Ali Guermazi and Frank W. Roemer: Radiography and Computed Tomography Imaging of Osteoarthritis 17: Walter Grassi, Tadashi Okano and Emilio Filippucci: Ultrasound in osteoarthritis and crystal-related arthropathies 18: David Hunter and Frank Roemer: Imaging - MRI 19: Leticia Alle Deveza, Changhai Ding, Xingzhong Jin, Xia Wang, Zhaohua Zhu and David Hunter: Laboratory tests 7. Management 20: Michael Doherty, Nigel Arden, Johannes Bijlsma, Nicola Dalbeth and David J. Hunter: Introduction: the comprehensive approach 21: Gillian Hawker, Anne Lyddiatt, Linda Li, Dawn Stacey, Susan Jaglal, Sarah Munce and Esther Waugh: Patient information strategies for decision making and management of osteoarthritis 22: Kim L Bennell, Ans Van Ginckel, Fiona Dobson and Rana S Hinman: Exercise for the person with osteoarthritis 23: Marius Henriksen, Robin Christensen, Berit L. Heitmann and Henning Bliddal: Weight loss 24: Christelle Nguyen and Francois Rannou: Addressing adverse mechanical factors 25: Joost Dekker, Daniel Bossen, Jasmijn Holla, Mariette de Rooij, Cindy Veenhof and Marike van der Leeden: Psychological strategies in osteoarthritis of the knee or hip 26: MA Holden, MJ Thomas and KS Dziedzic: Miscellaneous Physical Therapies 27: Dr. A. Abhishek and Prof. M. Doherty,: Placebo, nocebo and contextual effects 8. Pharmacological therapies 28: Dr A Abhishek, Dr Adrian Jones and Professor Michael Doherty: Topical pharmacologic treatments 29: Bernard Bannwarth and Francis Berenbaum: Systemic analgesics (including paracetamol and opioids) 30: Lee S. Simon and Marc C. Hochberg: Non-steroidal anti-inflammatory drugs 31: Allen D Sawitzke and Daniel O Clegg: Supplements for the treatment of Osteoarthritis 32: Nigel Arden and Terence O'Neill: Intra-articular injection therapy 9. Surgery 33: Andrew Price, Paul Monk and David Beard: Arthoplasty and its complications 34: Jonas Bloch Thorlund and L. Stefan Lohmander: Other surgical approaches in the management of osteoarthritis 10. Prospects for disease modification 35: Shirley Pei-Chun Yu and David John Hunter: Prospects for disease modification 11. Delivery of care 36: Caroline A Brand and Ilana N Ackerman: Delivery (organisation and outcome) 12. Guidelines 37: Weiya Zhang and Michael Doherty: Guidelines 13. Gout 38: Samantha Hider and Edward Roddy: Epidemiology of gout 39: Nicola Dalbeth: Pathophysiology of gout 40: Tony R Merriman: The genetic basis of gout 41: Tim L Jansen: Clinical presentation of gout 42: Eliseo Pascual and Francisca Sivera: Laboratory investigations in gout 43: Robert T. Keenan, Sneha Pai and Naomi Schlesinger: Imaging of gout 44: Pascal Richette: Principles of gout management 45: Puja Khanna: Treatment of acute gout 46: Fernando Perez-Ruiz, Irati Urionaguena and Sandra P. Chinchilla: Long-term management of gout 47: Thomas Bardin: Asymptomatic hyperuricaemia - to treat or not to treat? 14. Calcium pyrophosphate crystal deposition 48: Dr A Abhishek and Professor Michael Doherty: Epidemiology and risk factors for calcium pyrophosphate deposition 49: Dr A Abhishek and Professor Michael Doherty: Pathophysiology of calcium pyrophosphate deposition 50: Dr A Abhishek and Professor Michael Doherty: Clinical features of calcium pyrophosphate crystal deposition 51: Dr A Abhishek and Professor Michael Doherty: Investigations of calcium pyrophosphate deposition 52: Dr A Abhishek and Professor Michael Doherty: Treatment of calcium pyrophosphate deposition 15. Basic calcium phosphates 53: Nicola Dalbeth: Basic calcium phosphates and osteoarthritis
Professor Michael Doherty MA MD FRCP FHEA is Professor of Rheumatology and Head of Division of Rheumatology, Orthopaedics and Dermatology, School of Medicine, University of Nottingham. His main research interests are osteoarthritis (OA), gout, calcium pyrophosphate crystal deposition (CPPD), placebo/contextual response and evidence based medicine. He has expertise in clinical and epidemiological studies, community-based clinical trials, systematic reviews and meta-analyses. He has over 300 original research publications and was awarded the OA Research Society International (OARSI) Clinical Research Award for 2012. He is a past editor of Annals of the Rheumatic Diseases (1992-99), has co-chaired EULAR Task Forces for recommendations for OA, gout and CPPD arthritis, and has been involved as a clinical expert in NICE appraisals for OA and gout. Professor David Hunter is a rheumatology clinician researcher whose main research focus has been clinical and translational research in osteoarthritis (OA). He is the Florance and Cope Chair of Rheumatology and Professor of Medicine at University of Sydney, and Staff Specialist at Royal North Shore Hospital and North Sydney Orthopaedic and Sports Medicine Centre. His research is focused on a number of key elements in OA including (but not limited to) the epidemiology of osteoarthritis, the application of imaging to better understand structure and function with application to both epidemiologic research and clinical trials, novel therapies in disease management and heath service system delivery of chronic disease management. He is an editor for leading international journals in his field. He has authored books on osteoarthritis and has over 350 publications in peer reviewed journals. Johannes (Hans) Bijlsma is professor of Rheumatology at the University of Utrecht, as well as at both Universities (VU and UVA) in Amsterdam. He was Head of the Department of Rheumatology and Immunology in Utrecht (1989-2013) and of the Amsterdam Rheumatology and immunology Center (2013-2015). His main research interests are osteoarthritis (OA), treatment strategies in rheumatoid arthritis and glucocorticoids. He has expertise in clinical and epidemiological studies, randomised controlled clinical trials in early RA, systematic reviews and meta-analyses. He has over 600 original research publications and was awarded the Jan van Breemen Award for his scientific work in the Netherlands (2015). He is an associate editor of Annals of the Rheumatic Diseases (2005 - ongoing), has co-chaired EULAR Task Forces for recommendations for OA and the use of glucocorticoids. He has been the chair of Education of EULAR, the coordinator of the EULAR online courses and is presently the President-elect of EULAR Nigel Arden is a Professor of Rheumatic Diseases and an International Leader in Epidemiology and predictive modelling and trial design. He has clinical and research expertise in osteoarthritis, arthroplasty and osteoporosis and has published numerous manuscripts based on the use of cohort and large routinely collected databases in musculoskeletal diseases and their treatment. His research interests focus on the epidemiology of musculoskeletal diseases, with a focus on Osteoarthritis and Osteoporosis. He is based in the Botnar Research Centre, University of Oxford with additional sessions at the MRC Lifecourse Epidemiology Unit at the University of Southampton. Professor Nicola Dalbeth is an academic rheumatologist who leads a clinical and laboratory programme of research in gout, an inflammatory arthritis of major significance to Aotearoa New Zealand. Her work focuses on understanding the impact and mechanisms of disease in gout. She is a founding member of the Counties Manukau District Health Board Maori Gout Action Group, and she was the Lead Clinical Advisor for the Gout Clinical Pathways (Greater Auckland Integrated Healthcare Network) and the national bpac Gout Treatment Guidelines. She has served as an Expert Panel member on the American College of Rheumatology Gout Management Guidelines, and is a steering committee member for the OMERACT gout working group and the ACR/EULAR gout classification project.
