Virology is in a sense both one of the most important precursors and one of the most significant beneficiaries of structural and cellular molecular biology. Numerous breakthroughs in our understanding of the molecular interactions of viruses with host cells are ready for translation into medically important applications such as the prevention and treatment of viral infections. This book collects a wide variety of examples of frontline research into molecular aspects of viral infections from virological, immunological, cell- and molecular-biological, structural, and theoretical perspectives.
Unity in Diversity: Shared Mechanism of Entry Among Paramyxoviruses Jean-Louis Palgen, Eric M. Jurgens, Anne Moscona, Matteo Porotto and Laura M. Palermo Alphavirus Entry into Host Cells Ricardo Vancini, Raquel Hernandez and Dennis Brown The Mechanism of HCV Entry into Host Cells Florian Douam, Dimitri Lavillette and François-Loïc Cosset The Evolution of HIV Interactions with Coreceptors and Mannose C-type lectin Receptors Marie Borggren and Marianne Jansson A Game of Numbers: The Stoichiometry of Antibody-mediated Neutralization of Flavivirus Infection Theodore C. Pierson and Michael S. Diamond TRIM21-dependent Intracellular Antibody Neutralization of Virus Infection William A. McEwan and Leo C. James Picornavirus-host Interactions to Construct Viral Secretory Membranes Alexander L. Greninger Retroviral Factors Promoting Infectivity Emilia Cristiana Cuccurullo, Chiara Valentini and Massimo Pizzato The Cytoplasmic Tail of Retroviral Envelope Glycoproteins Philip R. Tedbury and Eric O. Freed Molecular Determinants of the Ratio of Inert to Infectious Virus Particles P.J. Klasse The Role of Chance in Primate Lentiviral infectivity: From Protomer to Host Organism Roland R. Regoes and Carsten Magnus Virus-encoded 7 Transmembrane Receptors Ann-Sofie Mølleskov-Jensen, Martha Trindade Oliveira, Helen Elizabeth Farrell and Nick Davis-Poynter EBV, the Human Host and the 7TM Receptors: Defense or Offense? Kristine Niss Arfelt, Suzan Fares and Mette M. Rosenkilde
