Medicinal Chemistry Approaches to Malaria and Other Tropical Diseases

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Kelly Chibale (University of Cape Town, South Africa) Rui Moreira (Universidade de Lisboa, Portugal)

Medicinal Chemistry Approaches to Malaria and Other Tropical Diseases

Kelly Chibale (University of Cape Town, South Africa), Rui Moreira (Universidade de Lisboa, Portugal)

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English

Academic Press Inc
25 October 2019

Diseases & disorders; Pharmacology; Tropical medicine; Organic chemistry

Series: Annual Reports in Medicinal Chemistry

Medicinal Chemistry Approaches to Malaria and Other Tropical Disease, Volume 53 in the Annual Reports in Medicinal Chemistry series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

Volume editor: Kelly Chibale (University of Cape Town South Africa), Rui Moreira (Universidade de Lisboa, Portugal)
Imprint: Academic Press Inc
Country of Publication: United States
Dimensions: Height: 229mm, Width: 152mm,
Weight: 500g
ISBN: 9780128198667
ISBN 10: 0128198664
Series: Annual Reports in Medicinal Chemistry
Pages: 232
Publication Date: 25 October 2019
Audience: Professional and scholarly , Undergraduate
Format: Hardback
Publisher's Status: Active

1. A decade of malaria phenotypic screenings: Key lessons on the discovery and development of new antimalarial drugs Esther Fernández, María Isabel Castellote, María Jesús Chaparro, Beatriz Díaz, Jorge Fernández, Mariola Gordo, Laura de las Heras, María Luisa León, Lourdes Rueda and Félix Calderón 2. Medicinal chemistry progression of antimalarial hits from phenotypic whole cell screening of SoftFocus libraries Peter M. Cheuka, Godfrey Mayoka, John Okombo and Kelly Chibale 3. The hybrid antimalarial approach Princy Gupta, Lovepreet Singh and Kamaljit Singh 4. Dealing with schistosomiasis: Current drug discovery strategies Sandra Gemma, Stefano Federico, Simone Brogi, Margherita Brindisi, Stefania Butini and Giuseppe Campiani 5. Shortcuts to schistosomiasis drug discovery: The state-of-the-art José T. Moreira-Filho, Rafael F. Dantas, Mário R. Senger, Arthur C. Silva, Dulcinea M. B. Campos, Eugene Muratov, Floriano P. Silva-Junior, Carolina H. Andrade and Bruno J. Neves 6. Multicomponent reactions: A mighty journey partner for infectious tropical disease drug discovery Diego Muñoz-Torrero, Rodolfo Lavilla, F. Javier Pérez-Areales and Ouldouz Ghashghaei

Kelly Chibale is a full Professor of Organic Chemistry at the University of Cape Town (UCT) where he holds the Neville Isdell Chair in African-centric Drug Discovery and Development. He is also a Full Member of the UCT Institute of Infectious Disease & Molecular Medicine, a Tier 1 South Africa Research Chair in Drug Discovery, founding Director of the South African Medical Research Council (SAMRC) Drug Discovery and Development Research Unit at UCT and the Founder and Director of the UCT Drug Discovery and Development Centre (H3D). Kelly obtained his PhD in Synthetic Organic Chemistry from the University of Cambridge in the UK (1989-1992). This was followed by postdoctoral stints at the University of Liverpool in the UK (1992-94) and at the Scripps Research Institute in the USA (1994-96). He was a Sandler Sabbatical Fellow at the University of California San Francisco (2002), a US Fulbright Senior Research Scholar at the University of Pennsylvania School of Medicine (2008) and a Visiting Professor at Pfizer in the UK (2008).